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For those seeking to treat pigmentation issues, Cosmelan and Dermamelan are top options. They target melanin to improve pigmentation. **Understanding the Differences Between Cosmelan and Dermamelan** – **Strength and Suitability**: With more potent ingredients, Dermamelan addresses deeper pigmentation issues, while Cosmelan is suitable for mild to moderate pigmentation. – ** Obagi Nu-Derm for Use**: Milder pigmentation, such as sun spots, can be treated with Cosmelan, while persistent pigmentation issues respond better to Dermamelan. **Steps in the Cosmelan and Dermamelan Treatment** 1. **Clinic-Based Mask Application**: A clinic-based mask application initiates the treatment, worn for several hours. 2. **Home Care**: Once the mask phase is over, a home care routine begins, with strict sun avoidance to enhance and sustain skin improvement. **Results and Common Side Effects** – **Results**: Results may be noticeable in the first week, and continues to clear pigmentation over time. – **Side Effects**: Redness, peeling, and sensitivity are common initial reactions, during the initial treatment phase. Talking to a professional will ensure the right treatment for your needs.